| Player | Team | AB | TB | SLG |
|---|---|---|---|---|
| Mike Trout | Albuquerque | 540 | 383 | 0.709 |
| Dominic Smith | Montana | 494 | 341 | 0.690 |
| Fernando Tatis Jr | Ohio | 627 | 420 | 0.670 |
| Freddie Freeman | Foscoe | 566 | 379 | 0.670 |
| Manny Machado | Brooklyn | 678 | 440 | 0.649 |
| DJ LeMahieu | Kankakee | 584 | 378 | 0.647 |
| Juan Soto | Brooklyn | 445 | 278 | 0.625 |
| Nelson Cruz | Albuquerque | 508 | 309 | 0.608 |
| Travis d'Arnaud | Colorado | 488 | 296 | 0.607 |
| Alex Dickerson | Boise | 432 | 261 | 0.604 |
| Luke Voit | Kansas City | 614 | 365 | 0.594 |
| Marcell Ozuna | Orlando | 621 | 368 | 0.593 |
| Jose Ramirez | Foscoe | 593 | 349 | 0.589 |
| Ronald Acuna | Fraser | 465 | 267 | 0.574 |
| Wilmer Flores | Southland | 581 | 327 | 0.563 |
| Paul Goldschmidt | Pea Ridge | 547 | 303 | 0.554 |
| Michael Conforto | Southland | 592 | 327 | 0.552 |
| Trevor Story | Montana | 682 | 374 | 0.548 |
| Robbie Grossman | Colorado | 496 | 266 | 0.536 |
| Joey Votto | Kankakee | 446 | 239 | 0.536 |