| Player | Team | AB | TB | SLG |
|---|---|---|---|---|
| Brandon Belt | Oak Lawn | 435 | 280 | 0.644 |
| Jose Abreu | Oak Lawn | 647 | 412 | 0.637 |
| Luke Voit | Milwaukee | 604 | 367 | 0.608 |
| Fernando Tatis Jr | Elko | 642 | 379 | 0.590 |
| Juan Soto | Oak Lawn | 444 | 262 | 0.590 |
| Manny Machado | Wisc. Rapids | 644 | 376 | 0.584 |
| Trea Turner | Wisc. Rapids | 689 | 391 | 0.567 |
| Mike Trout | Peculiar | 598 | 337 | 0.564 |
| Michael Conforto | Peculiar | 603 | 333 | 0.552 |
| Ronald Acuna | El Paso | 470 | 251 | 0.534 |
| Bryce Harper | El Paso | 439 | 227 | 0.517 |
| Ian Happ | Chicago | 465 | 240 | 0.516 |
| Rougned Odor | Peculiar | 507 | 258 | 0.509 |
| Chris Taylor | Elko | 536 | 261 | 0.487 |
| Jose Ramirez | Wisc. Rapids | 603 | 293 | 0.486 |
| Jeimer Candelario | Milwaukee | 543 | 259 | 0.477 |
| Brandon Crawford | El Paso | 486 | 222 | 0.457 |
| Donovan Solano | Wisc. Rapids | 539 | 245 | 0.455 |
| Matt Olson | Peculiar | 494 | 220 | 0.445 |
| Yoan Moncada | Elko | 566 | 251 | 0.443 |