| Player | Team | 2B |
|---|---|---|
| Dominic Smith | Montana | 69 |
| Freddie Freeman | Foscoe | 56 |
| Jose Ramirez | Foscoe | 49 |
| Jeff McNeil | Brooklyn | 48 |
| Jake Cronenworth | Tacoma | 48 |
| Christian Walker | Ohio | 48 |
| Maikel Franco | Arizona | 47 |
| Manny Machado | Brooklyn | 46 |
| Paul Goldschmidt | Pea Ridge | 46 |
| Cavan Biggio | Dakota | 46 |
| Robbie Grossman | Colorado | 42 |
| Dansby Swanson | Boise | 41 |
| Jose Iglesias | Albuquerque | 40 |
| J.D. Martinez | Kankakee | 40 |
| David Fletcher | Pea Ridge | 39 |
| Corey Seager | Foscoe | 38 |
| Eloy Jimenez | Brooklyn | 38 |
| Trea Turner | South Iowa | 38 |
| Jeimer Candelario | Kankakee | 37 |
| Brandon Belt | Albuquerque | 37 |