| Player | Team | RBI |
|---|---|---|
| Mike Trout | Riverside | 141 |
| Manny Machado | Havana | 138 |
| George Springer | Gallup | 134 |
| Jose Abreu | Boston | 130 |
| Trea Turner | Sterling | 129 |
| Jose Ramirez | Albuquerque | 126 |
| Wil Myers | Jacksonville | 125 |
| Teoscar Hernandez | Guildford | 124 |
| Fernando Tatis Jr | Tampa | 123 |
| Luke Voit | Kansas City | 122 |
| A.J. Pollock | Jacksonville | 121 |
| Wilmer Flores | New Jersey | 117 |
| Eloy Jimenez | New York | 113 |
| Dominic Smith | Las Vegas | 110 |
| Marcell Ozuna | Guildford | 108 |
| Edward Olivares | Syracuse | 105 |
| Franmil Reyes | Manhattan | 104 |
| Kole Calhoun | Tampa | 103 |
| Salvador Perez | Las Vegas | 102 |
| Eddie Rosario | New Jersey | 102 |