| Player | Team | RBI |
|---|---|---|
| George Springer | Gallup | 134 |
| Jose Abreu | Boston | 130 |
| Fernando Tatis Jr | Tampa | 123 |
| Luke Voit | Kansas City | 122 |
| Wilmer Flores | New Jersey | 117 |
| Eloy Jimenez | New York | 113 |
| Dominic Smith | Las Vegas | 110 |
| Franmil Reyes | Manhattan | 104 |
| Kole Calhoun | Tampa | 103 |
| Salvador Perez | Las Vegas | 102 |
| Eddie Rosario | New Jersey | 102 |
| Corey Seager | St. Louis | 99 |
| Nelson Cruz | Las Vegas | 98 |
| Freddie Freeman | Las Vegas | 93 |
| Dansby Swanson | Manhattan | 91 |
| Orlando Arcia | Boston | 91 |
| Maikel Franco | Las Vegas | 90 |
| Evan Longoria | Gallup | 88 |
| Mookie Betts | New York | 88 |
| Brandon Nimmo | Boston | 86 |