| Player | Team | 2B |
|---|---|---|
| Christian Walker | Ohio | 48 |
| Paul Goldschmidt | Pea Ridge | 46 |
| Cavan Biggio | Dakota | 46 |
| Dansby Swanson | Boise | 41 |
| Jose Iglesias | Albuquerque | 40 |
| J.D. Martinez | Kankakee | 40 |
| David Fletcher | Pea Ridge | 39 |
| Trea Turner | South Iowa | 38 |
| Jeimer Candelario | Kankakee | 37 |
| Brandon Belt | Albuquerque | 37 |
| Donovan Solano | Herefordshire | 37 |
| Mark Canha | Pea Ridge | 35 |
| Luis Robert | South Iowa | 35 |
| Myles Straw | Boise | 35 |
| Nick Senzel | Ohio | 34 |
| Anthony Rendon | Boise | 33 |
| Austin Nola | Dakota | 33 |
| Rafael Devers | Dakota | 33 |
| DJ LeMahieu | Kankakee | 31 |
| Marcell Ozuna | Orlando | 30 |