| Player | Team | 2B |
|---|---|---|
| Christian Walker | Ohio | 48 |
| Jose Iglesias | Albuquerque | 40 |
| J.D. Martinez | Kankakee | 40 |
| Trea Turner | South Iowa | 38 |
| Jeimer Candelario | Kankakee | 37 |
| Brandon Belt | Albuquerque | 37 |
| Luis Robert | South Iowa | 35 |
| Nick Senzel | Ohio | 34 |
| DJ LeMahieu | Kankakee | 31 |
| Marcell Ozuna | Orlando | 30 |
| Kyle Tucker | Ohio | 30 |
| Fernando Tatis Jr | Ohio | 29 |
| Orlando Arcia | Orlando | 29 |
| Jose Abreu | Orlando | 28 |
| JaCoby Jones | Kankakee | 27 |
| Mike Moustakas | South Iowa | 26 |
| Cody Bellinger | Orlando | 26 |
| Dylan Moore | South Iowa | 25 |
| Mike Trout | Albuquerque | 25 |
| Starlin Castro | Albuquerque | 24 |