| Player | Team | 2B |
|---|---|---|
| Dominic Smith | Las Vegas | 52 |
| Jose Abreu | Boston | 50 |
| Freddie Freeman | Las Vegas | 45 |
| Michael Brantley | California | 43 |
| Jose Iglesias | Las Vegas | 42 |
| Starling Marte | New Jersey | 41 |
| Willy Adames | Las Vegas | 39 |
| Cesar Hernandez | California | 38 |
| Jeff McNeil | Tampa | 37 |
| Gio Urshela | New York | 36 |
| Jesus Aguilar | Gallup | 36 |
| Michael Conforto | New Jersey | 36 |
| Robbie Grossman | Kansas City | 35 |
| Maikel Franco | Las Vegas | 35 |
| Ke'Bryan Hayes | New York | 34 |
| Andrew McCutchen | New York | 34 |
| Dansby Swanson | Manhattan | 34 |
| Salvador Perez | Las Vegas | 32 |
| Paul Goldschmidt | California | 32 |
| Austin Meadows | California | 31 |