| Player | Team | 2B |
|---|---|---|
| Jose Abreu | Boston | 50 |
| Gio Urshela | New York | 36 |
| Jesus Aguilar | Gallup | 36 |
| Robbie Grossman | Kansas City | 35 |
| Ke'Bryan Hayes | New York | 34 |
| Andrew McCutchen | New York | 34 |
| Dansby Swanson | Manhattan | 34 |
| Cavan Biggio | Boston | 30 |
| Alec Bohm | Kansas City | 30 |
| Mike Zunino | Manhattan | 27 |
| Mookie Betts | New York | 27 |
| Ji-Man Choi | New York | 27 |
| Dylan Carlson | Manhattan | 26 |
| Xander Bogaerts | Gallup | 26 |
| Evan Longoria | Gallup | 25 |
| Franmil Reyes | Manhattan | 25 |
| Cody Bellinger | Boston | 25 |
| Ty France | Boston | 24 |
| Jose Altuve | Gallup | 24 |
| Kurt Suzuki | Gallup | 23 |