| Player | Team | HR |
|---|---|---|
| Fernando Tatis Jr | Elko | 58 |
| Luke Voit | Milwaukee | 58 |
| Jose Abreu | Oak Lawn | 57 |
| Mike Trout | Peculiar | 49 |
| Manny Machado | Wisc. Rapids | 49 |
| Rougned Odor | Peculiar | 48 |
| Matt Olson | Peculiar | 37 |
| Ian Happ | Chicago | 37 |
| Michael Conforto | Peculiar | 36 |
| Ronald Acuna | El Paso | 36 |
| Trea Turner | Wisc. Rapids | 34 |
| Bryce Harper | El Paso | 33 |
| Salvador Perez | Milwaukee | 33 |
| Brandon Belt | Oak Lawn | 33 |
| Luis Robert | Oak Lawn | 32 |
| Jared Walsh | El Paso | 32 |
| Kole Calhoun | Elko | 32 |
| Josh Bell | El Paso | 31 |
| Freddie Freeman | Dayton | 30 |
| Anthony Rizzo | Monet | 30 |