| Player | Team | 2B |
|---|---|---|
| Francisco Lindor | Milwaukee | 38 |
| Michael Conforto | Peculiar | 36 |
| Trea Turner | Wisc. Rapids | 36 |
| Manny Machado | Wisc. Rapids | 36 |
| Donovan Solano | Wisc. Rapids | 34 |
| Jose Ramirez | Wisc. Rapids | 34 |
| Jeimer Candelario | Milwaukee | 33 |
| Ronald Acuna | El Paso | 33 |
| Nick Markakis | Milwaukee | 32 |
| Ty France | Peculiar | 31 |
| Brandon Crawford | El Paso | 30 |
| Jorge Mateo | El Paso | 28 |
| Salvador Perez | Milwaukee | 28 |
| Nick Ahmed | Peculiar | 27 |
| J.D. Martinez | Wisc. Rapids | 26 |
| Adam Eaton | Chicago | 26 |
| Joey Wendle | Chicago | 25 |
| Eduardo Escobar | El Paso | 25 |
| Josh Reddick | Peculiar | 23 |
| Javier Baez | El Paso | 22 |