| Player | Team | HR |
|---|---|---|
| Luke Voit | Milwaukee | 58 |
| Mike Trout | Peculiar | 49 |
| Manny Machado | Wisc. Rapids | 49 |
| Rougned Odor | Peculiar | 48 |
| Matt Olson | Peculiar | 37 |
| Ian Happ | Chicago | 37 |
| Michael Conforto | Peculiar | 36 |
| Ronald Acuna | El Paso | 36 |
| Trea Turner | Wisc. Rapids | 34 |
| Bryce Harper | El Paso | 33 |
| Salvador Perez | Milwaukee | 33 |
| Jared Walsh | El Paso | 32 |
| Josh Bell | El Paso | 31 |
| Jose Ramirez | Wisc. Rapids | 30 |
| Eddie Rosario | Chicago | 30 |
| Joc Pederson | Wisc. Rapids | 28 |
| Sean Murphy | Chicago | 25 |
| Brandon Crawford | El Paso | 25 |
| Gary Sanchez | El Paso | 24 |
| Michael Brosseau | Peculiar | 23 |