| Player | Team | SHO |
|---|---|---|
| Shane Bieber | Kankakee | 4 |
| Yu Darvish | Boise | 3 |
| Lance Lynn | Pea Ridge | 2 |
| Zac Gallen | Orlando | 2 |
| Aaron Nola | Portland | 2 |
| Dane Dunning | Pea Ridge | 1 |
| Zack Greinke | Albuquerque | 1 |
| Trevor Bauer | Ohio | 1 |
| Dallas Keuchel | South Iowa | 1 |
| Austin Gomber | Albuquerque | 1 |
| Chris Bassitt | Dakota | 1 |
| Tyler Glasnow | Dakota | 1 |
| Masahiro Tanaka | Boise | 1 |