| Player | Team | R |
|---|---|---|
| Kyle Freeland | Gallup | 185 |
| Zack Godley | New York | 172 |
| Rick Porcello | New York | 154 |
| Trevor Rogers | New York | 152 |
| Anibal Sanchez | New York | 147 |
| Jordan Lyles | St. Louis | 143 |
| Matthew Boyd | Gallup | 124 |
| Jesus Luzardo | Las Vegas | 118 |
| Masahiro Tanaka | Las Vegas | 115 |
| Alex Cobb | Boston | 113 |
| Chris Paddack | Gallup | 110 |
| Logan Webb | Gallup | 109 |
| Zack Wheeler | Las Vegas | 109 |
| Frankie Montas | Gallup | 108 |
| Taijuan Walker | Manhattan | 107 |
| Danny Duffy | St. Louis | 106 |
| Max Scherzer | California | 106 |
| Brady Singer | New Jersey | 102 |
| Ryan Yarbrough | Tampa | 101 |
| Chad Kuhl | Tampa | 100 |