| Player | Team | H |
|---|---|---|
| Kyle Freeland | Chicago | 290 |
| Kyle Hendricks | Arizona | 288 |
| Aaron Civale | Tacoma | 269 |
| German Marquez | Brooklyn | 244 |
| Zack Wheeler | Fraser | 229 |
| Martin Perez | Chicago | 223 |
| Luke Weaver | Chicago | 221 |
| Framber Valdez | Foscoe | 212 |
| Marco Gonzales | Foscoe | 206 |
| Jon Lester | Southland | 206 |
| Anthony DeSclafani | Tacoma | 204 |
| Max Scherzer | Foscoe | 201 |
| Brady Singer | Kansas City | 195 |
| Jesus Luzardo | Fraser | 194 |
| Gerrit Cole | Tacoma | 188 |
| Dylan Bundy | Kansas City | 186 |
| Trevor Williams | Chicago | 185 |
| Adam Wainwright | Montana | 181 |
| Kyle Gibson | Montana | 181 |
| Garrett Richards | Kansas City | 179 |