| Player | Team | H |
|---|---|---|
| Justus Sheffield | South Iowa | 217 |
| Tyler Anderson | South Iowa | 211 |
| Griffin Canning | Orlando | 210 |
| Zack Greinke | Albuquerque | 207 |
| Jose Berrios | Ohio | 201 |
| Brett Anderson | Orlando | 200 |
| Dallas Keuchel | South Iowa | 200 |
| Zac Gallen | Orlando | 191 |
| Blake Snell | Orlando | 190 |
| Jordan Lyles | Kankakee | 190 |
| James Paxton | Ohio | 187 |
| Jake Arrieta | Albuquerque | 176 |
| Logan Webb | Albuquerque | 174 |
| Shane Bieber | Kankakee | 149 |
| Tommy Milone | Ohio | 147 |
| Trevor Bauer | Ohio | 146 |
| Jorge Lopez | Orlando | 145 |
| Zach Plesac | South Iowa | 143 |
| Ryan Yarbrough | Kankakee | 142 |
| Kevin Gausman | Kankakee | 139 |