| Player | Team | W |
|---|---|---|
| Aaron Nola | Sterling | 23 |
| Jacob deGrom | Sterling | 21 |
| Dinelson Lamet | Sterling | 21 |
| Carlos Carrasco | Riverside | 18 |
| Lance Lynn | Riverside | 18 |
| Gerrit Cole | Guildford | 18 |
| Luis Castillo | Havana | 18 |
| Corbin Burnes | Jacksonville | 17 |
| Zac Gallen | California | 17 |
| Pablo Lopez | New York | 16 |
| Lucas Giolito | Las Vegas | 16 |
| Zack Wheeler | Las Vegas | 15 |
| Kenta Maeda | Kansas City | 15 |
| Griffin Canning | New Jersey | 15 |
| Brady Singer | New Jersey | 15 |
| Zach Davies | Albuquerque | 15 |
| Zach Plesac | Sterling | 15 |
| Brandon Woodruff | Malibu | 14 |
| German Marquez | Malibu | 14 |
| Dallas Keuchel | California | 14 |