| Player | Team | GS |
|---|---|---|
| Seth Lugo | Amarillo | 37 |
| Kyle Gibson | Detroit | 34 |
| Aaron Nola | Burlington | 34 |
| Rick Porcello | Phoenix | 34 |
| Logan Webb | Amarillo | 33 |
| Gerrit Cole | Burlington | 33 |
| Kyle Hendricks | Connecticut | 33 |
| German Marquez | Clinton | 32 |
| Cole Hamels | Clinton | 32 |
| Jake Odorizzi | Amarillo | 31 |
| Mike Minor | Connecticut | 28 |
| Austin Voth | Burlington | 28 |
| Marco Gonzales | Orlando | 28 |
| Brady Singer | Orlando | 28 |
| Trevor Williams | Amarillo | 28 |
| Spencer Turnbull | Niagara Falls | 28 |
| Zac Gallen | Torrance Beach | 27 |
| Yu Darvish | Torrance Beach | 27 |
| Zach Davies | Clinton | 27 |
| Tanner Roark | Detroit | 27 |