| Player | Team | SHO |
|---|---|---|
| Dinelson Lamet | Clinton | 3 |
| Yu Darvish | Torrance Beach | 3 |
| Zach Davies | Clinton | 2 |
| Yusei Kikuchi | Niagara Falls | 2 |
| Clayton Kershaw | Connecticut | 1 |
| Steven Brault | Detroit | 1 |
| Brad Wieck | Clinton | 1 |
| Taijuan Walker | Orlando | 1 |
| Josh A. Smith | Phoenix | 1 |
| Jose Berrios | Torrance Beach | 1 |
| Jon Lester | Orlando | 1 |
| Aaron Nola | Burlington | 1 |
| Gerrit Cole | Burlington | 1 |
| Jacob deGrom | Huntington Beach | 1 |
| Zac Gallen | Torrance Beach | 1 |
| Jesus Luzardo | Huntington Beach | 1 |