| Player | Team | GS |
|---|---|---|
| Antonio Senzatela | El Paso | 33 |
| Shane Bieber | Peculiar | 33 |
| Trevor Bauer | Peculiar | 32 |
| Carlos Carrasco | Peculiar | 31 |
| Frankie Montas | Wisc. Rapids | 31 |
| Zack Greinke | Wisc. Rapids | 31 |
| Chris Bassitt | Chicago | 31 |
| Martin Perez | Chicago | 31 |
| Mike Fiers | Chicago | 30 |
| Zach Eflin | Chicago | 30 |
| Anibal Sanchez | Wisc. Rapids | 30 |
| Aaron Civale | El Paso | 30 |
| Hyun Jin Ryu | Wisc. Rapids | 28 |
| Adrian Houser | Chicago | 28 |
| Johnny Cueto | Milwaukee | 27 |
| Ryan Yarbrough | El Paso | 27 |
| Sonny Gray | Peculiar | 25 |
| Dylan Bundy | Milwaukee | 25 |
| John Means | El Paso | 23 |
| Nathan Eovaldi | El Paso | 22 |