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Had this problem
I have had this problem... here is what I have found works for handling this glitch.
Set your default manager options only through the front office NOT through the schedule page.  When I do this... my defaults seem to stick better.
Now whenever you open a game to set the lineup this default should show up... even if you have already submitted the game lineup with differnt settings... it thinks you are re-submitting so it gives you the defaults again.
Hope this helps.
Cameron.  Bluenoses-RT1-99.  Arrows-RT1-98.