according to Mike and the preponents of this game, IF you want aggressive baserunning set it to the conservetive side.......in my, so far 5 yrs, experience with this game, and with all 3 of my teams........it doesn't matter which one you set it to....my players stop at 3rd 90% of the time no matter what I set it to. As far as getting picked off 2nd, I don't know if the baserunning settings hve to do with that.