| Player | Team | HR |
|---|---|---|
| Luke Voit | Kansas City | 48 |
| George Springer | Gallup | 46 |
| Jose Abreu | Boston | 45 |
| Eddie Rosario | New Jersey | 45 |
| Wilmer Flores | New Jersey | 42 |
| Ronald Acuna | St. Louis | 40 |
| Fernando Tatis Jr | Tampa | 37 |
| Xander Bogaerts | Gallup | 35 |
| Evan Longoria | Gallup | 34 |
| Kole Calhoun | Tampa | 34 |
| Mike Zunino | Manhattan | 34 |
| Mookie Betts | New York | 34 |
| DJ LeMahieu | Tampa | 33 |
| Colin Moran | New Jersey | 32 |
| Corey Seager | St. Louis | 32 |
| Nelson Cruz | Las Vegas | 32 |
| Dansby Swanson | Manhattan | 32 |
| Andrew McCutchen | New York | 31 |
| Jesse Winker | New Jersey | 30 |
| Eloy Jimenez | New York | 30 |